Escape from Patagonia is a gaucho-western film set in the tumultuous Patagonia of late nineteenth century. It's a story of survival, based on real facts from the personal diary of the Argentinian pioneer Francisco P. Moreno.

The film follows Bruna, a young actress who is going through a period of deep sadness and melancholy after breaking up with her boyfriend

Father Javier lives a fractured existence: on one side, he helps families who've witnessed miracles, and on the other he belongs to a trio of excommunicated priests who hunt the possessed down to exorcise them under their own terms: with Bibles, fire and shotguns.

Damiana is a married couple who, on a visit to Cambodia, are shaken by the revelation that the woman (Laura Nevole), sick with terminal cancer, makes to her husband (Juan José Vidal): she She lived in that country in the past, fell in love with a Khmer and had a child with him, something that her current partner was completely unaware of.