Dan McDowell, a pathetic 20 something, is in love with Lilly, a girl who can't stand the sight of him. But he may have some hope after all, with the help of his friend and roommate, Satan - who has an ulterior motive to get a penis of his own and take over the world. Dans quest for love is haunted by Lilly's estranged and abusive Boyfriend, Da'Louis. Meanwhile, Satan's plans to conquer the world are closely followed by Archangels Michael and Gabriel.

Fates align as a moody non-believer meets the woman of his dreams, and both of their groups of friends have to deal with the consequences.