In a dystopian, post-pandemic world crippled by a global fertility crisis, an aging smuggler struggles to protect a runaway teenager and her baby from ruthless criminals, while trying to complete his run for his vicious employers.

Decades after his career as a tobacco advertising icon, Bryan Burns’ life is in ruins. After his mother dies of lung cancer, he is tormented by a talking cigarette on an anti-smoking billboard. He snaps and transforms into the Ribspreader, a killer stalking the city, extinguishing smokers and cutting out their lungs to make his macabre smoking jacket.