East Shinjuku Night High School has students with various challenges. Delinquent Taketo is trapped in a negative spiral. Filipina-Japanese Angela struggles with schoolwork, while Kasumi spends all her class hours in the infirmary. Shozo had to leave school to work in his youth. With guidance from their new science teacher, Fujitake, they work on an experiment for an academic conference.

After the battle against Zogu was over, both Gamu and Fujimiya began to live normal lives until another threat arrives on Earth - a surviving monster soldier of Zogu's army named Gakuzom.