A priest and a harbor patrol chief must work together to try and stop the evil behind a possessed boat that begins hunting down and killing the locals of a small lakeside community.

A mafia drug lord has unleashed a new, highly addictive stimulant on the streets called HT25, derived from sharks held captive in a secret lab, and which causes monstrous side effects. After an explosion and leak at the lab, an army of mutated, bloodthirsty sharks and other creatures are set loose on the world.