As the Javits Center construction project ignites a battle for profit in early 1980s Hell's Kitchen, a generational rift threatens the uneasy peace between violent Irish gang the Westies and the Mafia, and draws FBI heat.

When a plague of unprecedented virulence sweeps the globe, the human race is all but wiped out. In the aftermath, as the great machine of civilization slowly and inexorably breaks down, only a few shattered survivors remain to struggle against the slide into extinction.