Zhen Yuan is a plump girl who fell in love with her high school senior, Dong Shen, both separated by a misunderstanding. Years later they reunited, Yuan become slim fashion model, Eva while Shen became a successful entrepreneur and chef.

Yi yi rescues a giant snake from an injury, afterwards the two become soulmates. But thugs and scientists want to change that. With yi yi and the snake fighting for their lives, will they escape the humans trying to hunt them down?