Patience Evans works in the Criminal Records Office in the city of York. She views the world in a unique way because she has a special gift – she is autistic. Patience has a special interest in solving puzzles and a secret fascination and talent for criminology—her unique perspective allows her to connect the dots through clues in a way others simply cannot. Detective Inspector Bea Metcalf recognizes her talents and takes her under her wing. Patience helps the police tackle a series of challenging cases by bringing her unique insight to crimefighting.

Addie, an autistic girl tries to get her village to make a memorial to the women who were put on trial for witchcraft there whom she believes were likely just autistic like her.