Lincoln Loud is an eleven-year-old boy who lives with ten sisters. With the help of his right-hand man Clyde, Lincoln finds new ways to survive in such a large family every day.

Ava, a spirited and imaginative girl, meets a curious animal named Lala. Together they go on a wild and magical adventure, where they encounter new animal friends and battle with the evil General Tiger for power over Cloud Land.

Desperate to get off Santa's Naughty List before Christmas, Lincoln resorts to hacking into the North Pole computers and putting himself on the nice list. But when the hack gets out of control, he ends up reversing the Naughty\/Nice lists around the world and turning the North Pole itself Naughty. Lincoln enlists his family to go to the North Pole and try to fix the mess he made. Teaming up with his new frenemy, Duncan, the elf who first put him on the naughty list, Lincoln and the Louds must battle a now evil Santa and his minions to save Christmas.