Formerly known as iconic, family-friendly interstate stops, many American motels have become places where transience and anonymity often go hand-in-hand. Murder at the Motel explores tragic murder cases set in motels and the pursuit to bring justice to the victims. The personal stories of the victims and of how the investigations unfolded are told from the perspective of family members and law enforcement officers who work tirelessly in their quest to solve these horrific crimes.

After Jack and Lucy rescue a woman from freezing cold in the middle of Scottish mountains, they come to realize that the woman is not who she says she is and that she has not the best intentions.

Steve, who is stuck in a corporate loophole, while a business trip he meets Amanda, an escort worker that has more to her than just the look, the drive and the sexuality.