Grace becomes addicted to opioids after suffering a sports injury. She's ready to leave her addiction behind under her mother's watch, but her past won't let her go: Richie kidnaps her in a motel room to sell her into human trafficking.

The week of her 50th birthday, Mindy, a divorced teacher, is going through a bonafide mid-life crisis as she prepares to host a long weekend at the lake with former boyfriend Sam, ex-husband Marc, and daughter Rita and her girlfriend Emily. In the process, Mindy begins to discover what it is she truly wants as she gets ready to start the next chapter.